Discussion:
[Gmod-gbrowse] No Gc content and six frame translation in GBrowse
Scott Cain
2014-04-25 15:01:58 UTC
Permalink
Hi Swetha,

Please ask questions like this on the gbrowse mailing list.

Did the directory.index file get created? Is there anything in the apache error log that might point to a problem? My first guess is a directory permission problem: the web server is unable the write in that directory.

Scott

Sent from my iPad
Hello Sir,
I am new bie to GBrowse. I followed the tutorial and installed GBrowse. Its not displaying the GC content and six frame translation when I added the fasta file in the database directory. I would be very thankful if you could help me with this.
-Swetha.
<quote author='Scott Cain'>
Hi Eman,
The most likely problem is that you tried to view the DNA and GC content
before you added the fasta file. When that happens, GBrowse will create
the directory.index file with nothing in it. GBrowse doesn't know that you
added a fasta file after that, so it continues to think there is nothing
there. The fix is to delete the directory.index file and try again.
Scott
I have followed all the steps (include the GC content and 6 frame
translation) in the *gbrowse 2.55* *tutorial.html* (on CentoOS 6.4
x86_64).
But, there are no "*GC content and 6 frame translation*" data displayed
as the snapscreen image.
(1)
http://202.200.111.222/cgi-bin/gb2/gbrowse/volvox/
(2)
*ll /var/lib/gbrowse2/databases/*
drwxrwxrwx 2 root root 4096 Jan 27 17:49 volvox
*ll /var/lib/gbrowse2/databases/volvox*
-rw-r--r-- 1 apache apache 12288 Jan 27 17:49 directory.index
*wc directory.index *
0 3 12288 directory.index
(3)
We have put several volvox*.gff3(including *volvox_remarks.gff3*) files
into /var/lib/gbrowse2/databases/volvox/
(4)
we have put *volvox.fa* into /var/lib/gbrowse2/databases/volvox/
*more /var/lib/gbrowse2/databases/volvox/volvox.fa*
ctgA
cattgttgcggagttgaacaacggcattaggaacacttccgtctctcacttttatacgat
tatgattggttctttagccttggtttagattggtagtagtagcggcgctaatgctacctg
......
(5)
*volvox.conf* in /etc/gbrowse2
[GENERAL]
db_adaptor = Bio::DB::SeqFeature::Store
db_args = -adaptor memory
-dir '/var/lib/gbrowse2/databases/volvox'
......
[DNA]
glyph = dna
global feature = 1
height = 40
do_gc = 1
gc_window = auto
fgcolor = red
axis_color = blue
strand = both
key = DNA/GC Content
......
Thanks.
eman
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply import
a virtual appliance and go from zero to informed in seconds.
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_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
--
------------------------------------------------------------------------
Scott Cain, Ph. D. scott at scottcain dot
net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
</quote>
http://generic-model-organism-system-database.450254.n5.nabble.com/there-are-no-GC-content-and-6-frame-translation-data-displayed-when-done-by-tutorial-tp5712123p5712126.html
_____________________________________
Sent from http://generic-model-organism-system-database.450254.n5.nabble.com
rayapadi swetha
2014-04-26 04:11:47 UTC
Permalink
Dear Sir,

Thank you for your reply.

The Directory.index was not created in the database directory and I gave
permission to the database directory. Even the restriction sites are not
displaying after updating .conf file with "*plugins = TrackDumper
Aligner RestrictionAnnotator*". I attached the screenshot of the page for
your reference.


*The error log shows*

[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] MSG: Could not open
/var/lib/gbrowse2/databases/streptococcus: No such file or directory,
referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Error::throw, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Root::Root::throw /usr/local/share/perl5/Bio/Root/Root.pm:486,
referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::IndexedBase::_calc_termination_length
/usr/local/share/perl5/Bio/DB/IndexedBase.pm:749, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::IndexedBase::_index_files
/usr/local/share/perl5/Bio/DB/IndexedBase.pm:633, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::IndexedBase::index_dir
/usr/local/share/perl5/Bio/DB/IndexedBase.pm:446, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::IndexedBase::new /usr/local/share/perl5/Bio/DB/IndexedBase.pm:361,
referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::SeqFeature::Store::memory::commit
/usr/local/share/perl5/Bio/DB/SeqFeature/Store/memory.pm:172, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::SeqFeature::Store::GFF3Loader::finish_load
/usr/local/share/perl5/Bio/DB/SeqFeature/Store/GFF3Loader.pm:352, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::SeqFeature::Store::Loader::load_fh
/usr/local/share/perl5/Bio/DB/SeqFeature/Store/Loader.pm:354, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::SeqFeature::Store::Loader::load
/usr/local/share/perl5/Bio/DB/SeqFeature/Store/Loader.pm:243, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::SeqFeature::Store::memory::post_init
/usr/local/share/perl5/Bio/DB/SeqFeature/Store/memory.pm:164, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::DB::SeqFeature::Store::new
/usr/local/share/perl5/Bio/DB/SeqFeature/Store.pm:395, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::DataBase::open_database
/usr/local/lib64/perl5/Bio/Graphics/Browser2/DataBase.pm:44, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::DataSource::open_database
/usr/local/lib64/perl5/Bio/Graphics/Browser2/DataSource.pm:997, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::DataSource::default_dbid
/usr/local/lib64/perl5/Bio/Graphics/Browser2/DataSource.pm:1033, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::RegionSearch::init_databases
/usr/local/lib64/perl5/Bio/Graphics/Browser2/RegionSearch.pm:125, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::Render::get_search_object
/usr/local/lib64/perl5/Bio/Graphics/Browser2/Render.pm:1234, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::PluginSet::configure
/usr/local/lib64/perl5/Bio/Graphics/Browser2/PluginSet.pm:88, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::Render::init_plugins
/usr/local/lib64/perl5/Bio/Graphics/Browser2/Render.pm:1279, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::Action::ACTION_retrieve_multiple
/usr/local/lib64/perl5/Bio/Graphics/Browser2/Action.pm:282, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::Render::asynchronous_event
/usr/local/lib64/perl5/Bio/Graphics/Browser2/Render.pm:430, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::Render::run_asynchronous_event
/usr/local/lib64/perl5/Bio/Graphics/Browser2/Render.pm:359, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
Bio::Graphics::Browser2::Render::run
/usr/local/lib64/perl5/Bio/Graphics/Browser2/Render.pm:277, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] STACK:
/var/apache/cgi-bin/gb2/gbrowse:54, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14]
-----------------------------------------------------------, referer:
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/

Can you please fix this error and help me with this. Awaiting for your
reply.

-Swetha Rayapadi
Post by Scott Cain
Hi Swetha,
Please ask questions like this on the gbrowse mailing list.
Did the directory.index file get created? Is there anything in the apache
error log that might point to a problem? My first guess is a directory
permission problem: the web server is unable the write in that directory.
Scott
Sent from my iPad
Hello Sir,
I am new bie to GBrowse. I followed the tutorial and installed GBrowse.
Its not displaying the GC content and six frame translation when I added
the fasta file in the database directory. I would be very thankful if you
could help me with this.
-Swetha.
<quote author='Scott Cain'>
Hi Eman,
The most likely problem is that you tried to view the DNA and GC content
before you added the fasta file. When that happens, GBrowse will create
the directory.index file with nothing in it. GBrowse doesn't know that
you
added a fasta file after that, so it continues to think there is nothing
there. The fix is to delete the directory.index file and try again.
Scott
I have followed all the steps (include the GC content and 6 frame
translation) in the *gbrowse 2.55* *tutorial.html* (on CentoOS 6.4
x86_64).
But, there are no "*GC content and 6 frame translation*" data displayed
as the snapscreen image.
(1)
http://202.200.111.222/cgi-bin/gb2/gbrowse/volvox/
(2)
*ll /var/lib/gbrowse2/databases/*
drwxrwxrwx 2 root root 4096 Jan 27 17:49 volvox
*ll /var/lib/gbrowse2/databases/volvox*
-rw-r--r-- 1 apache apache 12288 Jan 27 17:49 directory.index
*wc directory.index *
0 3 12288 directory.index
(3)
We have put several volvox*.gff3(including *volvox_remarks.gff3*) files
into /var/lib/gbrowse2/databases/volvox/
(4)
we have put *volvox.fa* into /var/lib/gbrowse2/databases/volvox/
*more /var/lib/gbrowse2/databases/volvox/volvox.fa*
ctgA
cattgttgcggagttgaacaacggcattaggaacacttccgtctctcacttttatacgat
tatgattggttctttagccttggtttagattggtagtagtagcggcgctaatgctacctg
......
(5)
*volvox.conf* in /etc/gbrowse2
[GENERAL]
db_adaptor = Bio::DB::SeqFeature::Store
db_args = -adaptor memory
-dir '/var/lib/gbrowse2/databases/volvox'
......
[DNA]
glyph = dna
global feature = 1
height = 40
do_gc = 1
gc_window = auto
fgcolor = red
axis_color = blue
strand = both
key = DNA/GC Content
......
Thanks.
eman
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
--
------------------------------------------------------------------------
Scott Cain, Ph. D. scott at scottcain
dot
net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
</quote>
http://generic-model-organism-system-database.450254.n5.nabble.com/there-are-no-GC-content-and-6-frame-translation-data-displayed-when-done-by-tutorial-tp5712123p5712126.html
_____________________________________
Sent from
http://generic-model-organism-system-database.450254.n5.nabble.com
rayapadi swetha
2014-04-29 04:03:28 UTC
Permalink
Dear Sir,

I am waiting for your reply. And also, I want to know, Do we need to get
the license or permission from GMOD to use the GBrowse in our database
which is underprogress for publication.

-Swetha


On Sat, Apr 26, 2014 at 9:41 AM, rayapadi swetha
Post by rayapadi swetha
Dear Sir,
Thank you for your reply.
The Directory.index was not created in the database directory and I gave
permission to the database directory. Even the restriction sites are not
displaying after updating .conf file with "*plugins = TrackDumper
Aligner RestrictionAnnotator*". I attached the screenshot of the page for
your reference.
*The error log shows*
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] MSG: Could not
open /var/lib/gbrowse2/databases/streptococcus: No such file or directory,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Root::Root::throw /usr/local/share/perl5/Bio/Root/Root.pm:486,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::_calc_termination_length
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::_index_files
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::index_dir
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::new /usr/local/share/perl5/Bio/DB/IndexedBase.pm:361,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::memory::commit
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::GFF3Loader::finish_load
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::Loader::load_fh
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::Loader::load
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::memory::post_init
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::new
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataBase::open_database
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataSource::open_database
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataSource::default_dbid
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::RegionSearch::init_databases
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::get_search_object
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::PluginSet::configure
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::init_plugins
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Action::ACTION_retrieve_multiple
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::asynchronous_event
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::run_asynchronous_event
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::run
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14]
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Can you please fix this error and help me with this. Awaiting for your
reply.
-Swetha Rayapadi
Post by Scott Cain
Hi Swetha,
Please ask questions like this on the gbrowse mailing list.
Did the directory.index file get created? Is there anything in the
apache error log that might point to a problem? My first guess is a
directory permission problem: the web server is unable the write in that
directory.
Scott
Sent from my iPad
Hello Sir,
I am new bie to GBrowse. I followed the tutorial and installed GBrowse.
Its not displaying the GC content and six frame translation when I added
the fasta file in the database directory. I would be very thankful if you
could help me with this.
-Swetha.
<quote author='Scott Cain'>
Hi Eman,
The most likely problem is that you tried to view the DNA and GC content
before you added the fasta file. When that happens, GBrowse will create
the directory.index file with nothing in it. GBrowse doesn't know that
you
added a fasta file after that, so it continues to think there is nothing
there. The fix is to delete the directory.index file and try again.
Scott
I have followed all the steps (include the GC content and 6 frame
translation) in the *gbrowse 2.55* *tutorial.html* (on CentoOS 6.4
x86_64).
But, there are no "*GC content and 6 frame translation*" data displayed
as the snapscreen image.
(1)
http://202.200.111.222/cgi-bin/gb2/gbrowse/volvox/
(2)
*ll /var/lib/gbrowse2/databases/*
drwxrwxrwx 2 root root 4096 Jan 27 17:49 volvox
*ll /var/lib/gbrowse2/databases/volvox*
-rw-r--r-- 1 apache apache 12288 Jan 27 17:49 directory.index
*wc directory.index *
0 3 12288 directory.index
(3)
We have put several volvox*.gff3(including *volvox_remarks.gff3*) files
into /var/lib/gbrowse2/databases/volvox/
(4)
we have put *volvox.fa* into /var/lib/gbrowse2/databases/volvox/
*more /var/lib/gbrowse2/databases/volvox/volvox.fa*
ctgA
cattgttgcggagttgaacaacggcattaggaacacttccgtctctcacttttatacgat
tatgattggttctttagccttggtttagattggtagtagtagcggcgctaatgctacctg
......
(5)
*volvox.conf* in /etc/gbrowse2
[GENERAL]
db_adaptor = Bio::DB::SeqFeature::Store
db_args = -adaptor memory
-dir '/var/lib/gbrowse2/databases/volvox'
......
[DNA]
glyph = dna
global feature = 1
height = 40
do_gc = 1
gc_window = auto
fgcolor = red
axis_color = blue
strand = both
key = DNA/GC Content
......
Thanks.
eman
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
--
------------------------------------------------------------------------
Scott Cain, Ph. D. scott at scottcain
dot
net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
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_____________________________________
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Scott Cain
2014-04-29 16:12:57 UTC
Permalink
Hi Swetha,

Are you using the memory adaptor? Generally that's not a good idea with a
production database as it tends to be really slow, but perhaps it won't be
bad with bacterial genomes since they're small.

I think there is a bug in the current release of BioPerl that's causing
this problem. I'd suggest installing BioPerl 1.6.901:

wget
http://backpan.perl.org/authors/id/C/CJ/CJFIELDS/BioPerl-1.6.901.tar.gz
tar zxvf BioPerl-1.6.901.tar.gz
cd BioPerl-1.6.901
perl Build.PL
./Build
./Build test
sudo ./Build install --uninst 1

The "--uninst 1" will make sure it removes other BioPerl modules from the
newer distribution.

For licensing: GBrowse is licensed under the Perl Artistic 2 license, which
(a legalese aside) means you can do what you want with it.

Scott
Post by rayapadi swetha
Dear Sir,
I am waiting for your reply. And also, I want to know, Do we need to get
the license or permission from GMOD to use the GBrowse in our database
which is underprogress for publication.
-Swetha
On Sat, Apr 26, 2014 at 9:41 AM, rayapadi swetha <
Post by rayapadi swetha
Dear Sir,
Thank you for your reply.
The Directory.index was not created in the database directory and I gave
permission to the database directory. Even the restriction sites are not
displaying after updating .conf file with "*plugins = TrackDumper
Aligner RestrictionAnnotator*". I attached the screenshot of the page
for your reference.
*The error log shows*
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] MSG: Could not
open /var/lib/gbrowse2/databases/streptococcus: No such file or directory,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Root::Root::throw /usr/local/share/perl5/Bio/Root/Root.pm:486,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::_calc_termination_length
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::_index_files
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::index_dir
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::new /usr/local/share/perl5/Bio/DB/IndexedBase.pm:361,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::memory::commit
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::GFF3Loader::finish_load
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::Loader::load_fh
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::Loader::load
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::memory::post_init
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::new
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataBase::open_database
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataSource::open_database
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataSource::default_dbid
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::RegionSearch::init_databases
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::get_search_object
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::PluginSet::configure
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::init_plugins
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Action::ACTION_retrieve_multiple
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::asynchronous_event
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::run_asynchronous_event
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::run
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14]
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Can you please fix this error and help me with this. Awaiting for your
reply.
-Swetha Rayapadi
Post by Scott Cain
Hi Swetha,
Please ask questions like this on the gbrowse mailing list.
Did the directory.index file get created? Is there anything in the
apache error log that might point to a problem? My first guess is a
directory permission problem: the web server is unable the write in that
directory.
Scott
Sent from my iPad
Hello Sir,
I am new bie to GBrowse. I followed the tutorial and installed
GBrowse. Its not displaying the GC content and six frame translation when I
added the fasta file in the database directory. I would be very thankful if
you could help me with this.
-Swetha.
<quote author='Scott Cain'>
Hi Eman,
The most likely problem is that you tried to view the DNA and GC
content
before you added the fasta file. When that happens, GBrowse will
create
the directory.index file with nothing in it. GBrowse doesn't know
that you
added a fasta file after that, so it continues to think there is
nothing
there. The fix is to delete the directory.index file and try again.
Scott
I have followed all the steps (include the GC content and 6 frame
translation) in the *gbrowse 2.55* *tutorial.html* (on CentoOS 6.4
x86_64).
But, there are no "*GC content and 6 frame translation*" data
displayed
as the snapscreen image.
(1)
MSG: Got a sequence without letters. Could not guess alphabet,
http://202.200.111.222/cgi-bin/gb2/gbrowse/volvox/
(2)
*ll /var/lib/gbrowse2/databases/*
drwxrwxrwx 2 root root 4096 Jan 27 17:49 volvox
*ll /var/lib/gbrowse2/databases/volvox*
-rw-r--r-- 1 apache apache 12288 Jan 27 17:49 directory.index
*wc directory.index *
0 3 12288 directory.index
(3)
We have put several volvox*.gff3(including *volvox_remarks.gff3*)
files
into /var/lib/gbrowse2/databases/volvox/
(4)
we have put *volvox.fa* into /var/lib/gbrowse2/databases/volvox/
*more /var/lib/gbrowse2/databases/volvox/volvox.fa*
ctgA
cattgttgcggagttgaacaacggcattaggaacacttccgtctctcacttttatacgat
tatgattggttctttagccttggtttagattggtagtagtagcggcgctaatgctacctg
......
(5)
*volvox.conf* in /etc/gbrowse2
[GENERAL]
db_adaptor = Bio::DB::SeqFeature::Store
db_args = -adaptor memory
-dir '/var/lib/gbrowse2/databases/volvox'
......
[DNA]
glyph = dna
global feature = 1
height = 40
do_gc = 1
gc_window = auto
fgcolor = red
axis_color = blue
strand = both
key = DNA/GC Content
......
Thanks.
eman
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply
import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
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--
------------------------------------------------------------------------
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scottcain dot
net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
</quote>
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_____________________________________
Sent from
http://generic-model-organism-system-database.450254.n5.nabble.com
--
------------------------------------------------------------------------
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net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
Scott Cain
2014-05-05 14:02:20 UTC
Permalink
Hi Swetha,

When this happens it is almost always because the name of the sequence in
the fasta file doesn't agree with the name of the sequence in the GFF file.
The name in the first column of the GFF file (the reference sequence) has
to be exactly the same (case matters) as the name after the ">" in the
fasta file. If they aren't the same, GBrowse can't tell that they go
together.

Scott



On Mon, May 5, 2014 at 7:17 AM, rayapadi swetha
Post by rayapadi swetha
Dear Sir,
I have installed BioPerl 1.3.901 and there is no bugs in error log. The
directory.index file is created. But, still GC content and 6-frame
translation is not working.
The example given in the tutorial is working good but not for our
organism. Actually, I placed the gff3 and faa file of that organism in a
folder which is downloaded from NCBI FTP in database folder. Do I need to
have any other file to be placed in the database folder to make it work?
Yours sincerely,
Swetha R G.
On Wed, Apr 30, 2014 at 9:08 AM, rayapadi swetha <
Post by rayapadi swetha
Dear Sir,
Thank you for your reply.
Let me try to install BioPerl 1.6.901.
-Swetha R G.
Post by Scott Cain
Hi Swetha,
Are you using the memory adaptor? Generally that's not a good idea with
a production database as it tends to be really slow, but perhaps it won't
be bad with bacterial genomes since they're small.
I think there is a bug in the current release of BioPerl that's causing
wget
http://backpan.perl.org/authors/id/C/CJ/CJFIELDS/BioPerl-1.6.901.tar.gz
tar zxvf BioPerl-1.6.901.tar.gz
cd BioPerl-1.6.901
perl Build.PL
./Build
./Build test
sudo ./Build install --uninst 1
The "--uninst 1" will make sure it removes other BioPerl modules from
the newer distribution.
For licensing: GBrowse is licensed under the Perl Artistic 2 license,
which (a legalese aside) means you can do what you want with it.
Scott
On Tue, Apr 29, 2014 at 12:03 AM, rayapadi swetha <
Post by rayapadi swetha
Dear Sir,
I am waiting for your reply. And also, I want to know, Do we need to
get the license or permission from GMOD to use the GBrowse in our database
which is underprogress for publication.
-Swetha
On Sat, Apr 26, 2014 at 9:41 AM, rayapadi swetha <
Post by rayapadi swetha
Dear Sir,
Thank you for your reply.
The Directory.index was not created in the database directory and I
gave permission to the database directory. Even the restriction sites are
not displaying after updating .conf file with "*plugins =
TrackDumper Aligner RestrictionAnnotator*". I attached the screenshot
of the page for your reference.
*The error log shows*
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14] MSG: Could not
open /var/lib/gbrowse2/databases/streptococcus: No such file or directory,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Root::Root::throw /usr/local/share/perl5/Bio/Root/Root.pm:486,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::_calc_termination_length
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::_index_files
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::index_dir
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::IndexedBase::new /usr/local/share/perl5/Bio/DB/IndexedBase.pm:361,
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::memory::commit
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::GFF3Loader::finish_load
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::Loader::load_fh
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::Loader::load
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::memory::post_init
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::DB::SeqFeature::Store::new
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataBase::open_database
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataSource::open_database
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::DataSource::default_dbid
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::RegionSearch::init_databases
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::get_search_object
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::PluginSet::configure
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::init_plugins
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Action::ACTION_retrieve_multiple
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::asynchronous_event
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::run_asynchronous_event
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Bio::Graphics::Browser2::Render::run
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
[Sat Apr 26 09:14:45 2014] [error] [client 10.132.1.14]
http://10.132.1.14/cgi-bin/gb2/gbrowse/Streptococcus%20penumoniae%20670-6B/
Can you please fix this error and help me with this. Awaiting for your
reply.
-Swetha Rayapadi
Post by Scott Cain
Hi Swetha,
Please ask questions like this on the gbrowse mailing list.
Did the directory.index file get created? Is there anything in the
apache error log that might point to a problem? My first guess is a
directory permission problem: the web server is unable the write in that
directory.
Scott
Sent from my iPad
Hello Sir,
I am new bie to GBrowse. I followed the tutorial and installed
GBrowse. Its not displaying the GC content and six frame translation when I
added the fasta file in the database directory. I would be very thankful if
you could help me with this.
-Swetha.
<quote author='Scott Cain'>
Hi Eman,
The most likely problem is that you tried to view the DNA and GC
content
before you added the fasta file. When that happens, GBrowse will
create
the directory.index file with nothing in it. GBrowse doesn't know
that you
added a fasta file after that, so it continues to think there is
nothing
there. The fix is to delete the directory.index file and try again.
Scott
I have followed all the steps (include the GC content and 6 frame
translation) in the *gbrowse 2.55* *tutorial.html* (on CentoOS 6.4
x86_64).
But, there are no "*GC content and 6 frame translation*" data
displayed
as the snapscreen image.
(1)
MSG: Got a sequence without letters. Could not guess alphabet,
http://202.200.111.222/cgi-bin/gb2/gbrowse/volvox/
(2)
*ll /var/lib/gbrowse2/databases/*
drwxrwxrwx 2 root root 4096 Jan 27 17:49 volvox
*ll /var/lib/gbrowse2/databases/volvox*
-rw-r--r-- 1 apache apache 12288 Jan 27 17:49 directory.index
*wc directory.index *
0 3 12288 directory.index
(3)
We have put several volvox*.gff3(including *volvox_remarks.gff3*)
files
into /var/lib/gbrowse2/databases/volvox/
(4)
we have put *volvox.fa* into /var/lib/gbrowse2/databases/volvox/
*more /var/lib/gbrowse2/databases/volvox/volvox.fa*
ctgA
cattgttgcggagttgaacaacggcattaggaacacttccgtctctcacttttatacgat
tatgattggttctttagccttggtttagattggtagtagtagcggcgctaatgctacctg
......
(5)
*volvox.conf* in /etc/gbrowse2
[GENERAL]
db_adaptor = Bio::DB::SeqFeature::Store
db_args = -adaptor memory
-dir '/var/lib/gbrowse2/databases/volvox'
......
[DNA]
glyph = dna
global feature = 1
height = 40
do_gc = 1
gc_window = auto
fgcolor = red
axis_color = blue
strand = both
key = DNA/GC Content
......
Thanks.
eman
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into
actionable
security intelligence. It gives you real-time visual feedback on
key
security issues and trends. Skip the complicated setup - simply
import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
--
------------------------------------------------------------------------
Scott Cain, Ph. D. scott at
scottcain dot
net
GMOD Coordinator (http://gmod.org/)
216-392-3087
Ontario Institute for Cancer Research
------------------------------------------------------------------------------
WatchGuard Dimension instantly turns raw network data into
actionable
security intelligence. It gives you real-time visual feedback on key
security issues and trends. Skip the complicated setup - simply
import
a virtual appliance and go from zero to informed in seconds.
http://pubads.g.doubleclick.net/gampad/clk?id=123612991&iu=/4140/ostg.clktrk
_______________________________________________
Gmod-gbrowse mailing list
https://lists.sourceforge.net/lists/listinfo/gmod-gbrowse
</quote>
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_____________________________________
Sent from
http://generic-model-organism-system-database.450254.n5.nabble.com
--
------------------------------------------------------------------------
Scott Cain, Ph. D. scott at scottcain
dot net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
--
------------------------------------------------------------------------
Scott Cain, Ph. D. scott at scottcain dot
net
GMOD Coordinator (http://gmod.org/) 216-392-3087
Ontario Institute for Cancer Research
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